Searchable abstracts of presentations at key conferences in endocrinology

ea0081p364 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

Acute hemolytic anemia due to glucose-6-phosphate dehydrogenase deficiency during treatment of diabetic ketoacidosis in an African American patient diagnosed with Ketosis-prone diabetes

Tsakalomatis Panagiotis-Nikolaos , Daraki Vasiliki , Vamvoukaki Rodanthi , Mytilinaiou Maria , Syntzanaki Eleni-Konstantina , Kontolaimaki Kalliopi , Chrysoulaki Maria , Sfakiotaki Maria , Venetsanaki Vasiliki , Bouki Katerina , Betsi Grigoria , Xekouki Paraskevi

Background: Diabetic ketoacidosis (DKA) has been associated with severe hemolysis in patients with Glucose-6-phosphate dehydrogenase (G6PD) deficiency after restoration of euglycemia. Less than 30 cases have been reported so far. The exact mechanism is not fully understood.Case presentation: A 35-year-old African American man presented to the emergency department with polyuria, polydipsia, abdominal pain and weight loss the last 15 days. Physical examina...

ea0099ep11 | Diabetes, Obesity, Metabolism and Nutrition | ECE2024

Diabetes mellitus due to reduced insulin secretion and exocrine pancreatic dysfunction in a patient with a mutation in the carboxyl-ester lipase gene outside the VNTR region

Venetsanaki Vasiliki , Daraki Vasiliki , Sertedaki Amalia , Mertzanian Anny , Pissadaki Evangelia , Vamvoukaki Rodanthi , Betsi Grigoria , Sfakiotaki Maria , Kanaka-Gantenbein Christina , Xekouki Paraskevi

Introduction: Mutations in the variable number of tandem repeats (VNTR) region of the carboxyl-ester lipase (CEL) gene can cause a very rare type of maturity-onset diabetes of the young (MODY 8) characterized by insulinopenic diabetes mellitus (DM) in early adulthood and slowly progressive exocrine pancreatic dysfunction. We present the unusual case of a patient with heterozygosity in a variant of CEL outside the VNTR region suffering from DM, dyslipidemia and exocrin...

ea0099ep244 | Pituitary and Neuroendocrinology | ECE2024

CTGF expression in human pituitary tumors and its association with their aggressiveness: preliminary data from an ongoing study

Vamvoukaki Rodanthi , Kyriakopoulos Georgios , Ntali Georgia , Vassiliadi Dimitra , Vlachou Panagiota , Koukoula Chrysoula , Barkas Konstantinos , Gkalonakis Ioannis , Tzanela Marinella , Andoniadou Cynthia , Xekouki Paraskevi

Background/Aim: Pituitary neuroendocrine tumors (PitNETs), although usually indolent, may display aggressive behavior. YAP/TAZ signalling has been linked to pituitary development and stem cell regulation, with a preliminary study from our group revealing elevated levels and nuclear localization of YAP/TAZ in non-functioning PitNETs (NF-PitNETs). CTGF, a YAP/TAZ target gene, encodes a secreted factor involved in proliferation and angiogenesis, that has been implicated ...

ea0081ep109 | Adrenal and Cardiovascular Endocrinology | ECE2022

Primary adrenal insufficiency due to bilateral adrenal hemorrhage-adrenal infarction in a patient with systemic lupus erythematosus and antiphospholipid syndrome

Bouki Katerina , Venetsanaki Vasiliki , Chrysoulaki Maria , Pateromichelaki Aikaterini , Bertsias George , Daraki Vasiliki , Spanakis Konstantinos , Betsi Grigoria , Sbyrakis Nikolaos , Sfakiotaki Maria , Kontolaimaki Kalliopi , Syntzanaki Eleni-Konstantina , Vamvoukaki Rodanthi , Tsakalomatis Panagiotis-Nikolaos , Sidiropoulos Prodromos , Xekouki Paraskevi

Background: Systemic lupus erythematosus (SLE) is an autoimmune disease with multisystem involvement and varied presentation but its association with adrenal insufficiency is rarely reported.Case presentation: A 30-year-old female presented to the emergency department with fever, lethargy and syncopal episodes during the last 48 h. She complained of general weakness, abdominal pain, nausea, vomiting, weight loss and anorexia for five months. Symptoms det...

ea0081ep629 | General Endocrinology | ECE2022

Epidemiological characteristics and psychological distress of well-controlled endocrine outpatients from Crete, Greece during the COVID-19 Pandemic: preliminary results of the EPITOME study.

Tsakalomatis Panagiotis-Nikolaos , Daraki Vasiliki , Roumeliotaki Theano , Betsi Grigoria , Chrysoulaki Maria , Sfakiotaki Maria , Syntzanaki Eleni- Konstantina , Vamvoukaki Rodanthi , Kontolaimaki Kalliopi , Venetsanaki Vasiliki , Nicolaou Kyriakos , Anomerianaki Polyxeni , Mavrakis George , Bouki Katerina , Goulia Panagiota , Xekouki Paraskevi

Aim: To explore the epidemiological characteristics and symptoms of psychological distress of well-controlled endocrine patients without a diagnosis of a psychiatric disorder attending the Endocrine outpatient clinic of the University Hospital, Heraklion, Crete, Greece during the COVID-19 pandemic. Methods: Eighty-four patients participated by completing questionnaires about demographics, endocrine diagnosis, covid infection, preventive measures, vaccination s...

ea0081ep630 | General Endocrinology | ECE2022

Comparison of perceived sufficiency of information, sources of information, worries about the pandemic and psychological distress between endocrinology patients and staff at the outpatient department of the university hospital, heraklion, crete greece: preliminary results of the EPITOME study

Daraki Vasiliki , Tsakalomatis Panagiotis- Nikolaos , Roumeliotaki Theano , Betsi Grigoria , Chrysoulaki Maria , Sfakiotaki Maria , Syntzanaki Eleni- Konstantina , Venetsanaki Vasiliki , Vamvoukaki Rodanthi , Kontolaimaki Kalliopi , Nicolaou Kyriakos , Mavrakis George , Anomerianaki Polyxeni , Bouki Katerina , Goulia Panagiota , Xekouki Paraskevi

Background: Psychological distress is elevated during pandemics such as the COVID-19 outbreak both in health care professionals and patients.Aim: To compare worries about the COVID-19 pandemic, need and sources of information, and psychological distress between endocrinology patients and staff at an outpatient department of the University Hospital, Heraklion, Crete, GreeceMethods: One hundred and four patients and sixty members of ...

ea0090p150 | Pituitary and Neuroendocrinology | ECE2023

Epidemiology, clinical presentation, treatment and outcome of acromegaly in the island of Crete, Greece. 27 years of follow up study

Chrysoulaki Maria , Vergou Stavrina , Maria Makri Artemis , Mpouhlaki Elpida , Michailidis Stefanos , DARAKI Vasiliki , Sfakiotaki Maria , betsi Grigoria , Kontolaimaki Kalliopi , Vamvoukaki Rodanthi , Sifaki-Pistola Dimitra , Lionis Christos , Goulielmos Georgios , Xekouki Paraskevi

Background: Acromegaly is a rare endocrine disorder due to growth hormone excess attributed to a pituitary tumor, in most cases. Epidemiological data of acromegaly are derived from national tumor registries or population studies while there are no published data in the Greek population except for a few small studies regarding treatment outcome.Methods: We carried out a retrospective ongoing observational study to determine the epidemiology, presentation ...

ea0073aep13 | Adrenal and Cardiovascular Endocrinology | ECE2021

Epidemiology, clinical course, and genetic analysis of pheochromocytomas/paragangliomas: A single centre tertiary care experience over 16 years from crete-greece

Chrysoulaki Maria , Fostira Florentia , Daraki Vasiliki , Betsi Grigoria , Sfakiotaki Maria , Mytilinaiou Maria , Bouki Katerina , Stathias Konstantinos , Spanakis Konstantinos , Panagiotis-Nikolaos Tsakalomatis , Eleni-Konstantina Syntzanaki , Kontolaimaki Kalliopi , Vamvoukaki Rodanthi , Nastos Konstantinos , Xekouki Paraskevi

BackgroundPheochromocytomas (PHOEs) and paragangliomas (PGLs) are rare neuroendocrine tumors originating from chromaffin cells. PHEO/PGL incidence ranges between 2–8/million, with 10–49% of these tumors being detected incidentally during imaging performed for other reasons. Up to 40% of PHEOs/PGLs patients have disease-specific germline pathogenic variants. This study aimed to investigate the epidemiology, clinical course, and genetic backgroun...

ea0099ep262 | Pituitary and Neuroendocrinology | ECE2024

Epidemiology, clinical presentation, treatment and outcome of acromegaly in the island of crete, greece: experience of 3 tertiary centers over a four decade period

Chrysoulaki Maria , Daraki Vasiliki , Sfakiotaki Maria , Tzoutzouraki Paraskevi , Floroskoufi Paraskevi , Betsi Grigoria , Vamvoukaki Rodanthi , Vergou Stavrina , Michailidis Stefanos , Maria Makri Artemis , Mpouhlaki Elpida , Spanoudaki Antonela , Goulielmos Georgios , Lionis Christos , Stamataki Katerina , Xekouki Paraskevi

Acromegaly is a rare and insidious endocrine disease, with increased morbidity and mortality mainly due to delayed diagnosis and inadequate control. There are many population studies assessing the epidemiology of acromegaly in Europe while in Greece, there are no published data except for a few small studies regarding treatment outcome.Aim: To determine the epidemiology, presentation and outcome in patients with acromegaly in Crete, Greece.<p class="...

ea0099ep355 | Thyroid | ECE2024

Increased psychological distress among patients with two or more endocrinopathies during Covid-19 pandemic: the EPITOME Study

Daraki Vasiliki , Roumeliotaki Theano , Tsakalomatis Panagiotis-Nikolaos , Betsi Grigoria , Sfakiotaki Maria , Chrysoulaki Maria , Syntzanaki Eleni-Konstantina , Venetsanaki Vasiliki , Vamvoukaki Rodanthi , Kontolaimaki Kalliopi , Makraki Eirini , Kopidakis Ioannis , Dimas Christos , Lioudaki Stella , Ioannou Christos , Krasagakis Konstantinos , Goulia Panagiota , Xekouki Paraskevi

Background: Psychological distress is elevated during pandemics such as the COVID-19 outbreak. Patients with diabetes mellitus (DM), are a particularly vulnerable risk group. However, data of the impact of other endocrinopathies on psychological status of patients during pandemics are lacking so far.Aim: To compare psychological distress about COVID-19 pandemic, between endocrine patients with a variety of endocrinopathies and patients with non-endocrine...